Oral EDTA -- An
Opinion
Life Flow One
The Solution For Heart Disease
by
Karl Loren
MOUNT
ROGERS CLINIC
Trout Dale, Virginia
MOUNT RAINIER CLINIC
Yelm,
Washington
By Elmer M. Cranton, M.D.
Over the years, oral chelation has been marketed in two ways—both deceptive.
High-potency formulas containing vitamins, antioxidants, amino acids and chelated minerals are advertised as "Oral Chelation." Although it is true that vitamin C and some amino acids found in food are weak chelators, those products are relatively inexpensive and can be purchased in any health food store, without the hype and without the high prices of the same products when sold as "oral chelation." People will naturally feel better while taking a high-potency vitamin preparation, but it is not chelation therapy.
Minerals used in nutritional supplements are often chelated (bound together) with amino acids to improve absorption, and the label may state "chelated." That is the reverse process of infusing a chelator like EDTA to remove toxins from the body. Most products marketed as "oral chelation" are nothing more than multiple vitamin/mineral supplements with excessively high prices.
One product being sold as "oral chelation" is honey with a tiny amount of EDTA as preservative. The amount of EDTA is so small that it has no therapeutic significance. This is another example of deceptive marketing.
There has recently been an upsurge of aggressive marketing and advertising for oral products that contain EDTA, such as garlic tablets and other nutritional supplements. Although only a small percentage of EDTA is absorbed by mouth, it is true that after taking such a product every day for a year or more the same total amount of EDTA as the amount received in a course of intravenous therapy can be assimilated. The problem is that 95% of the oral EDTA remains in the digestive tract, passes on through, and clings tightly to nutritional trace elements such as zinc, copper, manganese, and chromium, blocking their absorption and carrying them out of the body in the stool. Over time that can cause severe nutritional deficiencies.
Intravenous EDTA is usually given only 20 to 30 times in a year. It does remove essential nutritional trace elements from the body on the days when it is given—but those losses can easily be restored and pre-existing deficiencies replenished by supplementing during more than 300 days of the year when there is no EDTA in the body to counteract absorption or cause deficiencies.
One hundred percent of intravenous EDTA is absorbed on the day it is infused, allowing a full course of therapy to be administered on 20 to 30 days spread out over several months. Oral EDTA is so poorly absorbed that it must be taken every day, and there is never a time to make up the losses. It is also not possible to supplement with additional trace elements while taking EDTA by mouth because even more EDTA would then be trapped in the digestive tract, bound to nutritional elements, reducing absorption of both essential nutrients and EDTA.
EDTA by mouth has never been studied in a large group of people for a long enough period of time to determine the extent to which it contributes to nutritional deficiencies. Because it has never been studied in this way, it is just not possible to state that oral EDTA in therapeutic doses is safe when given for months at a time. To date, there is no good scientific data to prove that people who take therapeutic doses of EDTA by mouth for months on end do not become deficient in nutritional trace elements.
If studies exist of before-and-after body zinc balance, copper balance, manganese balance, etc., or similar information gathered during continuous oral EDTA treatment, I would be most interested in seeing them. I have never seen such data and I do not believe that it exists.
I have also never seen any convincing evidence that daily EDTA by mouth brings any benefit, in comparison to intermittent intravenous infusions. Marketing claims thus far are unsubstantiated by scientific evidence. I see only unsubstantiated advertising claims by those who profit from sales.
Until proven otherwise, I will continue to believe that it is irresponsible, and possibly dangerous, to promote oral EDTA as a treatment or preventive for heart disease, atherosclerosis, and other age-related diseases.
Mercury chelation is an exception to the above opinions. DMSA (dimercapto succinic acid) is available in capsules from pharmacies on a doctor’s prescription. DMSA is very effective by mouth to remove mercury from the body. In fact, oral DMSA is even more effective than EDTA and other intravenous chelators, including DMPS, for mercury detoxification.
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